Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.59 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054183 | 0.90 | ALDH1A1 (0.59) | PIM1PIM2KMT2AMEN1TP53 | |
| SCHEMBL30524280 | 0.90 | ALDH1A1 (0.59) | PIM1PIM2KMT2AMEN1TP53 | |
| SCHEMBL29054174 | 0.88 | ALDH1A1 (0.59) | KMT2AMEN1CYP3A4TP53BLM | |
| SCHEMBL210696 | 0.82 | HDAC1 (0.56) | KMT2AMEN1CYP3A4ALDH1A1MAPT | |
| SCHEMBL11193187 | 0.80 | PIM1 (0.64) | PIM1PIM2KMT2AMEN1CYP3A4 | |
| Furegrelate SCHEMBL10953582 | 0.80 | TP53 (0.77) | PIM1PIM2KMT2AMEN1CYP3A4 | |
| SCHEMBL30524276 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1TP53ALDH1A1KDM4E | |
| Furegrelate SCHEMBL10956224 | 0.79 | TP53 (0.76) | PIM1PIM2KMT2AMEN1CYP3A4 | |
| Furegrelate SCHEMBL10451458 | 0.79 | TP53 (0.76) | PIM1PIM2KMT2AMEN1CYP3A4 | |
| SCHEMBL5583428 | 0.77 | HIF1A (0.58) | KMT2AMEN1TP53ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | METHYLGENE INC. (CA) | 2007-09-13 | — | — | US | disclosed |
| US-7253204-B2 | Antiproliferative agents | METHYLGENE INC. (CA) | 2007-08-07 | — | — | US | disclosed |
| US-20050245518-A1 | Antiproliferative agents | METHYLGENE, INC. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | HDAC1, HDAC11, HDAC5 | PIM1 2009/4885PIM2 2680/4885KMT2A 68/4885 |
| US-20050245518-A1 | Antiproliferative agents | HDAC1, HDAC11, HDAC5 | PIM1 2462/4885PIM2 3102/4885KMT2A 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.