Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.44 |
| ▸ | PDE4A | P27815 | 9/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583511 | 0.87 | CA1 (0.59) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL500368 | 0.87 | CA1 (0.59) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL2527455 | 0.75 | PDE4B (0.72) | PDE3APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL12375128 | 0.75 | CA1 (0.59) | CA1CA2KLK5KLK1 | |
| SCHEMBL23701742 | 0.74 | CA1 (0.51) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL21821453 | 0.73 | CA1 (0.56) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL14363857 | 0.73 | CA1 (0.57) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL19605204 | 0.73 | CA1 (0.57) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL12475434 | 0.73 | CA1 (0.57) | CA1CA2PDE3AKLK5PDE4B | |
| SCHEMBL23701726 | 0.71 | CA1 (0.48) | CA1CA2PDE3AKLK5PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353133-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-20130059803-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CA1 4091/4885CA2 1368/4885PDE3A 4505/4885 |
| US-20130059803-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CA1 4091/4885CA2 1368/4885PDE3A 4505/4885 |
| US-20070155699-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | CA1 4091/4885CA2 1368/4885PDE3A 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.