Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.46 |
| ▸ | PYGM | P11217 | 3/20 | 0.45 |
| ▸ | TYMP | P19971 | 2/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880551 | 1.00 | P2RY2 (0.50) | P2RY2DNPH1P2RY6PYGMTYMP | |
| SCHEMBL8673051 | 0.91 | P2RY6 (0.56) | P2RY2DNPH1P2RY6PYGMP2RY14 | |
| SCHEMBL8038838 | 0.91 | P2RY6 (0.56) | P2RY2DNPH1P2RY6PYGMP2RY14 | |
| SCHEMBL2784568 | 0.86 | SLC28A1 (0.58) | P2RY2P2RY6P2RY14 | |
| SCHEMBL2784571 | 0.86 | SLC28A1 (0.58) | P2RY2P2RY6P2RY14 | |
| SCHEMBL2786473 | 0.83 | TYMS (0.60) | — | |
| SCHEMBL11876295 | 0.83 | TYMS (0.60) | — | |
| SCHEMBL11881949 | 0.83 | TYMS (0.60) | — | |
| SCHEMBL766555 | 0.83 | TYMS (0.60) | — | |
| SCHEMBL11876308 | 0.83 | TYMS (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425417-B1 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECH GMBH (DE) | 2007-10-31 | — | — | EP | disclosed |
| EP-0256400-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-09-23 | — | — | EP | disclosed |
| EP-0256400-A2 | Pyrimidine derivatives, their preparation and medicaments containing these derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-02-24 | — | — | EP | disclosed |