SCHEMBL2784568

SCHEMBL2784568

Cc1ccc(S(=O)(=O)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.58
SLC28A2 O43868 1/20 0.58
SLC29A1 Q99808 1/20 0.58
SLC28A3 Q9HAS3 1/20 0.58
P2RY6 Q15077 9/20 0.58
P2RY2 P41231 12/20 0.57
P2RY4 P51582 7/20 0.57
P2RY14 Q15391 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784571 1.00 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL19534565 0.90 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL11880551 0.86 P2RY2 (0.50) P2RY6P2RY2P2RY14
SCHEMBL5583994 0.86 P2RY2 (0.50) P2RY6P2RY2P2RY14
SCHEMBL14583149 0.85 P2RY14 (0.73) P2RY6P2RY2P2RY4P2RY14
SCHEMBL12015068 0.85 P2RY14 (0.73) P2RY6P2RY2P2RY4P2RY14
SCHEMBL14414535 0.85 P2RY14 (0.73) P2RY6P2RY2P2RY4P2RY14
SCHEMBL14027758 0.85 P2RY6 (0.58) P2RY6P2RY2P2RY4P2RY14
SCHEMBL14088634 0.85 P2RY14 (0.73) P2RY6P2RY2P2RY4P2RY14
SCHEMBL12361501 0.85 P2RY14 (0.73) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100291118-A1 Class of Gamma Delta T Cells Activators and Use Thereof INNATE PHARMA (FR) 2010-11-18 US disclosed
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject INNATE PHARMA, S.A. (FR) 2010-10-07 US disclosed
US-20100222306-A1 Class of Gamma Delta T Cells Activators and Use Thereof INNATE PHARMA, S.A. (FR) 2010-09-02 US disclosed
US-7767842-B2 Class of γδ T cells activators and use thereof INNATE PHARMA SA (FR) 2010-08-03 US disclosed
US-7683045-B2 Class of γδ T cells activators and use thereof INNATE PHARMA S.A. (FR) 2010-03-23 US disclosed
EP-1569656-B1 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2010-03-03 EP disclosed
EP-1761278-B1 ADJUVANT COMPOSITION AND METHODS FOR ITS USE INNATE PHARMA (FR) 2008-12-31 EP disclosed
US-20080207568-A1 Class of Gamma Delta T Cells Activators and Use Thereof INNATE PHARMA S.A. (FR) 2008-08-28 US disclosed
CN-101146575-A New class of gamma delta T cells activators and use thereof INNATE PHARMA SA (FR) 2008-03-19 CN disclosed
EP-1863572-A2 NEW CLASS OF T CELLS ACTIVATORS AND USE THEREOF Innate Pharma (FR) 2007-12-12 EP disclosed
CN-1890252-A Novel class of gamma delta T cell activators and uses thereof INNATE PHARMA (FR) 2007-01-03 CN disclosed
EP-1720567-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA Innate Pharma (FR) 2006-11-15 EP disclosed
WO-2006103568-A2 NEW CLASS OF Ϝδ T CELLS ACTIVATORS AND USE THEREOF INNATE PHARMA (FR) 2006-10-05 WO disclosed
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject INNATE PHARMA, S.A.S. (FR) 2006-08-31 US disclosed
EP-1689758-A2 NEW CLASS OF GAMMA DELTA T CELLS ACTIVATORS AND USE THEREOF Innate Pharma (FR) 2006-08-16 EP disclosed
WO-2005102385-A1 ADJUVANT COMPOSITION AND METHODS FOR ITS USE INNATE PHARMA (FR) 2005-11-03 WO disclosed
EP-1569656-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE Innate Pharma (FR) 2005-09-07 EP disclosed
WO-2005077411-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA INNATE PHARMA (FR) 2005-08-25 WO disclosed
WO-2005054258-A2 NEW CLASS OF GAMMA DELTA T CELLS ACTIVATORS AND USE THEREOF INNATE PHARMA (FR) 2005-06-16 WO disclosed
WO-2004050096-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject IFNG, IL2, ICOS SLC28A1 4031/4885SLC28A2 4129/4885SLC29A1 3345/4885
US-20080207568-A1 Class of Gamma Delta T Cells Activators and Use Thereof NFATC1, CD4, CD74 SLC28A1 4164/4885SLC28A2 4076/4885SLC29A1 3500/4885
US-20100291118-A1 Class of Gamma Delta T Cells Activators and Use Thereof CD4, IFNG, NFATC1 SLC28A1 4007/4885SLC28A2 4258/4885SLC29A1 3277/4885
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject IFNG, IL2, ICOS SLC28A1 4092/4885SLC28A2 4187/4885SLC29A1 3344/4885
US-20100222306-A1 Class of Gamma Delta T Cells Activators and Use Thereof NFATC1, CD4, CD74 SLC28A1 4164/4885SLC28A2 4076/4885SLC29A1 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.