Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Meglumine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meglumine SCHEMBL18270062 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL14126374 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL12195402 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL22641548 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL23363692 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL724392 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL23106596 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL20836266 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL23363691 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL22562873 | 1.00 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 74180 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746863-A1 | ENDOXIFEN COMPOSITIONS AND METHODS OF USE THEREOF AND SYNTHESIS THEREOF | Atossa Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| EP-3836899-B1 | CHEMOTHERAPEUTIC PHARMACEUTICAL SUSPENSION FOR ORAL DOSAGE | ONCOSOL LTD (GB) | 2026-05-27 | — | — | EP | claimed |
| CN-122075459-A | Application of alpha-hydroxy isocaproic acid in weight and lipid reduction | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075420-A | Imidazo [1,2-a ] pyridine derivative pharmaceutical composition and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075514-A | Use of glycogen phosphatase B agonists for the treatment of neurodegenerative diseases | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075488-A | Compound preparation for treating hypertension and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070132-A | Vortioxetine pharmaceutical composition and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2026101937-A1 | COMPOSITIONS COMPRISING (Z)-ENDOXIFEN AND A CDK4/6 INHIBITOR AND METHODS OF USE THEREOF | ATOSSA THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | claimed |
| WO-1984000420-A1 | NEW REAGENT FOR THE DIAGNOSTIC OF PARASITOSIS AND ALLERGIA, PROCESS FOR THE PREPARATION OF THIS NEW REAGENT AND PROCESS FOR THE DIAGNOSTIC OF PARASITOSIS AND ALLERGIA BY MEANS OF SAID REAGENT | PASTEUR INSTITUT (FR) | 1984-02-02 | — | — | WO | claimed |
| EP-0099812-A1 | Reagent for the diagnosis of parasitosis and allergies, method for the preparation of this reagent and method of diagnosing parasitosis and allergies using this reagent | INSTITUT PASTEUR (FR) | 1984-02-01 | — | — | EP | claimed |
| US-4396597-A | Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer | NYEGAARD & CO. A/S (NO) | 1983-08-02 | — | — | US | claimed |
| US-4327734-A | Therapeutic method of use for miniature detachable balloon catheter | BECTON, DICKINSON AND COMPANY, A CORP. OF NJ | 1982-05-04 | — | — | US | claimed |
| US-4278654-A | Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer | NYEGAARD & CO. A/S (NO) | 1981-07-14 | — | — | US | claimed |
| US-4069250-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1978-01-17 | — | — | US | claimed |
| US-4007166-A | Meglumine complexes of fungicidal polyene macrolide antibiotics and method of preparing same | KULBAKH VALTER OSVALDOVICH | 1977-02-08 | — | — | US | claimed |
| US-4002741-A | Meglumine complex fungicidal polyene macrolide antibiotic compositions and treatment method | KULBAKH VALTER OSVALDOVICH | 1977-01-11 | — | — | US | claimed |
| US-3953497-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1976-04-27 | — | — | US | claimed |