Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837054 | 0.89 | NPC1 (0.56) | NPC1RAB9AEPHX1MAPTLMNA | |
| SCHEMBL3080079 | 0.89 | NPC1 (0.56) | NPC1RAB9AEPHX1MAPTLMNA | |
| SCHEMBL1566071 | 0.87 | MAPT (0.53) | NPC1RAB9AEPHX1MAPTLMNA | |
| SCHEMBL539395 | 0.79 | DDB1 (0.46) | NPC1RAB9AEPHX1MAPTLMNA | |
| SCHEMBL3400048 | 0.79 | MAPT (0.61) | SMN1; SMN2NPC1RAB9AEPHX1MAPT | |
| SCHEMBL78145 | 0.79 | MAPT (0.61) | SMN1; SMN2NPC1RAB9AEPHX1MAPT | |
| SCHEMBL11526941 | 0.79 | MAPT (0.61) | SMN1; SMN2NPC1RAB9AEPHX1MAPT | |
| Hydrochloric Acid SCHEMBL1918398 | 0.77 | DDB1 (0.44) | NPC1RAB9AEPHX1MAPTLMNA | |
| SCHEMBL11526739 | 0.77 | MAPT (0.63) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL674674 | 0.77 | RAB9A (0.59) | SMN1; SMN2NPC1RAB9AEPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814875-A2 | IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE | The Regents of the University of California (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006045119-A2 | IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-04-27 | — | — | WO | disclosed |