⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193203 | 0.75 | — | — | |
| SCHEMBL9861244 | 0.69 | — | — | |
| SCHEMBL10777843 | 0.68 | — | — | |
| SCHEMBL10819074 | 0.67 | — | — | |
| SCHEMBL24838825 | 0.67 | — | — | |
| SCHEMBL10353184 | 0.67 | — | — | |
| SCHEMBL1412724 | 0.67 | — | — | |
| SCHEMBL3995563 | 0.67 | — | — | |
| SCHEMBL10778658 | 0.64 | — | — | |
| SCHEMBL1101946 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124459-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR | 石家庄以岭药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-120136868-A | Tricyclic fused heterocyclic PDE3/4 dual inhibitor and preparation method and application thereof | 石家庄以岭药业股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-20200181192-A1 | DISULFIDE BIOCONJUGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-06-11 | — | — | US | disclosed |
| US-7164047-B2 | Subjecting a 3-cyclopropyl-2,3-epoxypropionic acid ester to solvolysis in the presence of a base, treating the product of the solvolysis with an acid to obtain cyclopropylacetaldehyde, and reducing the obtained cyclopropylacetaldehyde; low cost, industrially advantageous | KURARAY CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20050020846-A1 | Subjecting a 3-cyclopropyl-2,3-epoxypropionic acid ester to solvolysis in the presence of a base, treating the product of the solvolysis with an acid to obtain cyclopropylacetaldehyde, and reducing the obtained cyclopropylacetaldehyde; low cost, industrially advantageous | KURARAY CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1445248-A1 | PROCESSES FOR PREPARATION OF CYCLOPROPYLETHANOL, CYCLO-PROPYLACETONITRILE AND INTERMEDIATES OF BOTH | KURARAY CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
| US-4714714-A | Arachidonic acid analogs | E. R. SQUIBB & SONS, INC. (US) | 1987-12-22 | — | — | US | disclosed |
| US-4599439-A | Arachidonic acid analogs | E. R. SQUIBB & SONS, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-3954730-A | ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |