⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861244 | 0.76 | — | — | |
| SCHEMBL24838825 | 0.75 | — | — | |
| SCHEMBL3995563 | 0.75 | — | — | |
| SCHEMBL5584563 | 0.75 | — | — | |
| SCHEMBL9019403 | 0.71 | — | — | |
| SCHEMBL9861821 | 0.65 | — | — | |
| SCHEMBL10777843 | 0.64 | — | — | |
| SCHEMBL10353184 | 0.63 | — | — | |
| SCHEMBL1412724 | 0.63 | — | — | |
| SCHEMBL24850609 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108911972-B | Racemization recovery method for by-product in resolution mother liquor of sitafloxacin intermediate | 武汉大学 | 2020-07-10 | — | — | CN | disclosed |
| US-6596898-B2 | Making a 2-fluoro-2-chlorocyclopropanecarboxylic acid derivative stereoselectively in high yield by reacting a diazoacetic acid derivative with 1-fluoro-1-chloroethylene using metal catalyst having chiral ligands | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| US-20010051750-A1 | PROCESS FOR PREPARING HALOGENATED CYCLOPROPANE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-12-13 | — | — | US | disclosed |
| EP-0858992-B1 | PROCESS FOR PRODUCING HALOGENATED CYCLOPROPANE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0712831-B1 | SELECTIVE DEHALOGENATION METHOD | DAIICHI SEIYAKU CO (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0858992-A1 | PROCESS FOR PRODUCING HALOGENATED CYCLOPROPANE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5780669-A | Selective dehalogenation process | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0712831-A1 | SELECTIVE DEHALOGENATION METHOD | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |