SCHEMBL5585372

SCHEMBL5585372

CC[C@@H](C(=O)O)C(=O)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.38
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA2 P00918 1/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2573659 1.00 ALDH1A1 (0.39) ALDH1A1TP53CHRM1AKR1A1CHRM3
SCHEMBL8460968 0.88 TSHR (0.37) ALDH1A1TDP1MEN1KMT2AFFAR3
SCHEMBL1177030 0.85 HDAC1 (0.41) ALDH1A1TP53CHRM1AKR1A1CHRM3
SCHEMBL15903570 0.82 MEN1 (0.32) ALDH1A1MEN1KMT2A
SCHEMBL4813785 0.81 GABRR1 (0.37) ALDH1A1TP53CHRM1AKR1A1CHRM3
SCHEMBL970305 0.79 ALDH1A1 (0.36) ALDH1A1TP53CHRM1AKR1A1CHRM3
Ethylmalonate SCHEMBL107241 0.78
SCHEMBL26668831 0.78 CHRM1 (0.36) ALDH1A1TP53CHRM1AKR1A1CHRM3
SCHEMBL1304663 0.77 CYP3A4 (0.39) HDAC1HDAC2CA2FFAR3
SCHEMBL1304726 0.77 CYP3A4 (0.36) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007013640-A1 Y2O3 FILM AND PROCESS FOR PRODUCING THE SAME SHOWA DENKO K.K. (JP) 2007-02-01 WO disclosed