Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.58 |
| ▸ | PPARA | Q07869 | 8/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585655 | 0.90 | GCGR (0.49) | PPARD | |
| SCHEMBL5585732 | 0.80 | KMT2A (0.43) | PPARDFFAR1 | |
| SCHEMBL5585686 | 0.77 | KMT2A (0.47) | FFAR1 | |
| SCHEMBL5585567 | 0.77 | ADRB2 (0.51) | PPARA | |
| SCHEMBL6243594 | 0.75 | PPARD (0.75) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL6237379 | 0.75 | PPARD (1.00) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL5585411 | 0.74 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL1553175 | 0.74 | PPARD (0.73) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL1553892 | 0.74 | PPARD (0.73) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL27671035 | 0.74 | PPARD (0.63) | PPARDPPARAPPARGFFAR1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20050065196-A1 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1452530-A1 | AZOLE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065196-A1 | Azole compound and medicinal use thereof | PTPN7, PTPN1, PTPN5 | PPARD 1925/4885PPARA 1524/4885PPARG 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.