⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034297 | 0.91 | — | — | |
| SCHEMBL27104074 | 0.86 | HSD17B10 (0.30) | — | |
| SCHEMBL6035318 | 0.78 | MEN1 (0.31) | — | |
| SCHEMBL2309236 | 0.76 | — | — | |
| SCHEMBL5009656 | 0.74 | HSD17B10 (0.31) | — | |
| SCHEMBL3769382 | 0.72 | — | — | |
| SCHEMBL2776396 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL10834338 | 0.72 | — | — | |
| SCHEMBL17002613 | 0.71 | — | — | |
| SCHEMBL1143924 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241009-B2 | Crosslinking of silicones presence of functionalized silicones | CALHOUN VISION, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1781212-A2 | CROSSLINKING OF SILICONES | Calhoun Vision, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006002201-A2 | CROSSLINKING OF SILICONES | CALHOUN VISION, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050018310-A1 | Crosslinking of silicones presence of functionalized silicones | RXSIGHT, INC. | 2005-01-27 | — | — | US | disclosed |