Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.88 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | SCD | O00767 | 1/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.61 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259147 | 0.89 | MEN1 (0.86) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL5585537 | 0.89 | MEN1 (0.70) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL1818544 | 0.89 | CSNK2A1 (1.00) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL5585937 | 0.84 | MEN1 (0.64) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL13206963 | 0.83 | SCD (0.82) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL12316832 | 0.83 | MEN1 (0.79) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11887633 | 0.83 | CSNK2A1 (0.78) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL13401539 | 0.83 | CSNK2A1 (0.78) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL20379817 | 0.81 | CSNK2A1 (0.75) | MEN1KMT2ACSNK2A1MAPTRAB9A | |
| SCHEMBL18029563 | 0.81 | NPC1 (0.72) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20050065196-A1 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1452530-A1 | AZOLE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065196-A1 | Azole compound and medicinal use thereof | PTPN7, PTPN1, PTPN5 | MEN1 3299/4885KMT2A 2589/4885CSNK2A1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.