Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585843 | 0.90 | EPHB4 (0.52) | ERBB4GAAALDH1A1KDREPHB4 | |
| SCHEMBL5959769 | 0.85 | EPHB4 (0.45) | POLBGAAKDREPHB4TEK | |
| SCHEMBL5599451 | 0.85 | KDR (0.43) | GAAALDH1A1KDREPHB4TEK | |
| SCHEMBL5600156 | 0.85 | EPHB4 (0.46) | ERBB4GAAALDH1A1KDREPHB4 | |
| SCHEMBL5592785 | 0.85 | EPHB4 (0.46) | GAAALDH1A1KDREPHB4TEK | |
| SCHEMBL5601036 | 0.85 | EPHB4 (0.46) | GAAALDH1A1KDREPHB4TEK | |
| SCHEMBL5586048 | 0.84 | ERBB4 (0.58) | POLBEGFRERBB4GAAALDH1A1 | |
| Ji-101 SCHEMBL5585996 | 0.84 | EPHB4 (0.46) | GAAALDH1A1KDREPHB4TEK | |
| Ji-101 SCHEMBL29375077 | 0.84 | EPHB4 (0.46) | GAAALDH1A1KDREPHB4TEK | |
| SCHEMBL5592763 | 0.84 | EPHB4 (0.46) | GAAALDH1A1KDREPHB4TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110416553-B | Proton membrane fuel cell catalyst, preparation method thereof and fuel cell system | 奇瑞商用车（安徽）有限公司 | 2023-12-01 | — | — | CN | claimed |
| EP-1858879-B1 | 1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY | GILEAD CONNECTICUT INC (US) | 2012-06-06 | — | — | EP | claimed |
| US-20060199846-A1 | Certain substituted ureas as modulators of kinase activity | GILEAD CONNECTICUT, INC. | 2006-09-07 | — | — | US | claimed |
| CN-118235272-A | Membrane-electrode assembly for fuel cell comprising linear porous silica nanoparticles, and fuel cell comprising the same | 可隆工业株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-115039262-B | Polymer electrolyte membrane and membrane-electrode assembly including the same | 可隆工业株式会社 | 2024-06-18 | — | — | CN | disclosed |
| CN-118176608-A | Membrane electrode assembly of fuel cell including plate-shaped porous silicon and fuel cell including the same | 可隆工业株式会社 | 2024-06-11 | — | — | CN | disclosed |
| CN-118160120-A | Reinforced composite membrane for fuel cell, method of manufacturing the same, and membrane electrode assembly including the same | 可隆工业株式会社 | 2024-06-07 | — | — | CN | disclosed |
| EP-3451428-B1 | FUEL CELL MEMBRANE-ELECTRODE ASSEMBLY | KOLON INC (KR) | 2023-08-02 | — | — | EP | disclosed |
| CN-111418104-B | Polymer electrolyte membrane, method of preparing the same, and membrane electrode assembly including the same | 可隆工业株式会社 | 2023-05-16 | — | — | CN | disclosed |
| US-20230006232-A1 | METHOD FOR MANUFACTURING POLYMER ELECTROLYTE MEMBRANE, AND ELECTROLYTE MEMBRANE MANUFACTURED BY SAME | KOLON INDUSTRIES, INC. (KR) | 2023-01-05 | — | — | US | disclosed |
| US-20220416284-A1 | POLYMER ELECTROLYTE MEMBRANE AND MEMBRANE ELECTRODE ASSEMBLY COMPRISING SAME | KOLON INDUSTRIES, INC. (KR) | 2022-12-29 | — | — | US | disclosed |
| US-20140186742-A1 | CATALYST FOR FUEL CELL, AND ELECTRODE FOR FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL SYSTEM INCLUDING SAME | HYUNDAI MOTOR COMPANY (KR) | 2014-07-03 | — | — | US | disclosed |
| US-20120141913-A1 | POLYMER ELECTROLYTE MEMBRANE FOR POLYMER ELECTROLYTE FUEL CELL, METHOD OF MANUFACTURING THE SAME AND POLYMER ELECTROLYTE FUEL CELL SYSTEM INCLUDING THE SAME | IUCF-HYU (Industry-University Cooperation Foundati on Hanyang University (KR) | 2012-06-07 | — | — | US | disclosed |
| EP-1858879-B1 | 1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY | GILEAD CONNECTICUT INC (US) | 2012-06-06 | — | — | EP | disclosed |
| EP-1858879-B1 | 1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY | GILEAD CONNECTICUT INC (US) | 2012-06-06 | — | — | EP | disclosed |
| EP-2397478-A1 | 1,3-diaryl substituted ureas as modulators of kinase activity. | CGI Pharmaceuticals, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2397478-A1 | 1,3-diaryl substituted ureas as modulators of kinase activity. | CGI Pharmaceuticals, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-1858879-A1 | 1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY | CGI Pharmaceuticals, Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| US-20060199846-A1 | Certain substituted ureas as modulators of kinase activity | GILEAD CONNECTICUT, INC. | 2006-09-07 | — | — | US | disclosed |
| WO-2006076593-A1 | 1,3-DIARYL SUBSTITUTED UREAS AS MODULATORS OF KINASE ACTIVITY | CGI PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199846-A1 | Certain substituted ureas as modulators of kinase activity | UCK2, CHUK, AXL | POLB 3113/4885EGFR 98/4885ERBB4 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.