Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344598 | 0.96 | ALOX15 (0.59) | ALOX15TSHRCASP1CA12CA2 | |
| Perchlorate SCHEMBL7111057 | 0.85 | NOTUM (0.53) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL9284900 | 0.83 | CA12 (0.61) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL10263007 | 0.80 | CA12 (0.57) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL7902821 | 0.80 | CA12 (0.57) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL1360325 | 0.80 | CA12 (0.62) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL17790966 | 0.80 | CA12 (0.57) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL1169513 | 0.80 | CA12 (0.57) | ALOX15TSHRCASP1CA12CA2 | |
| SCHEMBL15507350 | 0.78 | CA12 (0.55) | CA12CA2CA9CA1HDAC4 | |
| SCHEMBL2684521 | 0.78 | ALOX15 (0.96) | ALOX15TSHRCASP1HDAC4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| EP-1749003-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005116016-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-08 | — | — | WO | disclosed |
| WO-2003087052-A2 | DYES AND FLUORESCENT COMPOUNDS | TERPETSCHNIG EWALD A (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | ALOX15 448/4885TSHR 559/4885CASP1 3209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.