Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294871 | 0.89 | LMNA (0.74) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL19200948 | 0.88 | LMNA (0.63) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL18897541 | 0.88 | LMNA (0.93) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL7765946 | 0.85 | LMNA (0.67) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL2985725 | 0.84 | LMNA (1.00) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL30230194 | 0.84 | LMNA (1.00) | LMNABLMPTPN1MEN1CYP3A4 | |
| Squalane SCHEMBL4708649 | 0.84 | LMNA (1.00) | LMNABLMPTPN1MEN1CYP3A4 | |
| Squalane SCHEMBL15449 | 0.84 | LMNA (1.00) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL29030039 | 0.84 | LMNA (1.00) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL1269376 | 0.84 | LMNA (1.00) | LMNABLMPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1767627-A1 | ANTI-PERP ANTIBODY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |