Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821001 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3691473 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7055583 | 0.98 | PAK1 (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL10897324 | 0.92 | USP2 (0.46) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL284354 | 0.84 | GAA (0.53) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL10897831 | 0.83 | HPGD (0.39) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL11334284 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7049219 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL28590599 | 0.77 | GAA (0.50) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL26449578 | 0.77 | KDM4E (0.57) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1818347-B1 | A POLYURETHANE COMPOSITE, ITS PREPARATION AND USE | BAYER IP GMBH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-1818347-A1 | A POLYURETHANE COMPOSITE, ITS PREPARATION AND USE | Bayer MaterialScience AG (DE) | 2007-08-15 | — | — | EP | disclosed |