SCHEMBL5586209

SCHEMBL5586209

NP(O)Oc1ccc2c(c1)Oc1cc(O)ccc1C21OC(=O)c2cc(C(=O)O)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.55
MAPT P10636 3/20 0.53
MEN1 O00255 2/20 0.53
HTT P42858 2/20 0.53
KMT2A Q03164 2/20 0.53
HPGD P15428 2/20 0.53
CYP2C19 P33261 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
SMAD3 P84022 1/20 0.53
PRMT1 Q99873 1/20 0.53
ACE2 Q9BYF1 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KCNH2 Q12809 1/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
USP2 O75604 1/20 0.47
GSTP1 P09211 1/20 0.45
CYP3A4 P08684 1/20 0.43
ALOX12 P18054 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113888 0.93 FTO (0.52) FTOMAPTMEN1HTTKMT2A
SCHEMBL93531 0.87 FTO (0.72) FTOMAPTMEN1HTTKMT2A
SCHEMBL29838678 0.86 FTO (0.69) FTOMAPTMEN1HTTKMT2A
SCHEMBL29358729 0.86 FTO (0.69) FTOMAPTMEN1HTTKMT2A
SCHEMBL20095 0.86 FTO (0.69) FTOMAPTMEN1HTTKMT2A
SCHEMBL29996062 0.86 FTO (0.69) FTOMAPTMEN1HTTKMT2A
SCHEMBL31005263 0.86 FTO (0.63) FTOMAPTMEN1HTTKMT2A
SCHEMBL23158785 0.85 FTO (0.67) FTOMAPTMEN1HTTKMT2A
Ammonia Solution, Strong SCHEMBL29083296 0.85 FTO (0.67) FTOMAPTMEN1HTTKMT2A
Water SCHEMBL25247555 0.85 FTO (0.67) FTOMAPTMEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130165350-A1 SURFACE LINKERS FOR ARRAY SYNTHESIS AFFYMETRIX, INC. (US) 2013-06-27 US disclosed
US-7176297-B2 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2007-02-13 US disclosed
US-20040234788-A1 Photoactivateable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. 2004-11-25 US disclosed
US-6773888-B2 ARRAY OF OLIGONUCLEOTIDES; FUNCTIONALIZED POLYMER, A PHOTOACTIVATABLE SILANE COMPOUND CAPABLE OF PHOTOCHEMICALLY CROSS-LINKING TO SAID FUNCTIONALIZED POLYMER. AFFYMETRIX, INC. 2004-08-10 US disclosed
WO-2003087166-A2 PHOTOACTIVATABLE SILANE COMPOUNDS AND METHODS FOR THEIR SYNTHESIS AND USE AFFYMETRIX, INC. (US) 2003-10-23 WO disclosed
US-20030194715-A1 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194715-A1 Photoactivatable silane compounds and methods for their synthesis and use PCNA, GMNN, LSS FTO 2036/4885MAPT 4263/4885MEN1 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.