Methionine

Methionine

SCHEMBL5586887

CSCC[C@H](N)C(=O)O.NCCC[C@H](N)C(=O)O

nearest known ligand 0.78

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.62
NOS3 P29474 4/20 0.47
NOS1 P29475 4/20 0.47
NOS2 P35228 4/20 0.47
CYP2C19 P33261 2/20 0.47
THPO P40225 1/20 0.47
BHMT Q93088 6/20 0.47
BHMT2 Q9H2M3 1/20 0.47
RNPEP Q9H4A4 1/20 0.46
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ARG1 P05089 1/20 0.43
ARG2 P78540 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL8902674 1.00 GSR (0.62) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL938951 0.95 GSR (0.71) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL1345092 0.95 GSR (0.71) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL8720001 0.95 GSR (0.71) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL1345091 0.95 GSR (0.71) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL10491088 0.95 GSR (0.71) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL27480207 0.95 GSR (0.71) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL6665159 0.93 GSR (0.69) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL6574898 0.93 GSR (0.69) GSRNOS3NOS1NOS2CYP2C19
Lysine SCHEMBL6574892 0.93 GSR (0.69) GSRNOS3NOS1NOS2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1499303-A4 MULTI-PHASE, MULTI-COMPARTMENT CAPSULAR SYSTEM MILLER FRED H (US) 2007-07-25 EP disclosed
EP-1499303-A2 MULTI-PHASE, MULTI-COMPARTMENT CAPSULAR SYSTEM Miller, Fred H. (US) 2005-01-26 EP disclosed
WO-2003086267-A2 MULTI-PHASE, MULTI-COMPARTMENT CAPSULAR SYSTEM MILLER FRED H (US) 2003-10-23 WO disclosed
US-5593970-A ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING BIOCHEM PHARMA INC. (CA) 1997-01-14 US disclosed