⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096879 | 0.89 | — | — | |
| SCHEMBL4715 | 0.82 | — | — | |
| SCHEMBL4594 | 0.77 | — | — | |
| SCHEMBL11501665 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL23772 | 0.75 | — | — | |
| SCHEMBL237512 | 0.73 | POLB (0.59) | — | |
| SCHEMBL3646422 | 0.73 | POLB (0.46) | — | |
| SCHEMBL293768 | 0.73 | CXCR4 (0.56) | — | |
| SCHEMBL23011510 | 0.71 | CXCR4 (0.48) | — | |
| SCHEMBL43582 | 0.71 | CXCR4 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4033 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184614-A | Substituted benzo five-membered unsaturated heterocyclic compounds, and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-14 | — | — | CN | claimed |
| US-20240190891-A1 | PYRIDO OXAZINE AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-06-13 | — | — | US | claimed |
| WO-2024120454-A1 | BIS-PHOSPHATIDYL AMINE COMPOUNDS CONTAINING MULTIPLE TERTIARY AMINO STRUCTURES, AND COMPOSITION AND USE THEREOF | 北京大学 | 2024-06-13 | — | — | WO | claimed |
| CN-118146262-A | Bi-phosphatidyl amide compound containing multiple tertiary amino structures, composition and application thereof | 北京大学 | 2024-06-07 | — | — | CN | claimed |
| CN-113372267-B | C-Met kinase inhibitor | 鲁南制药集团股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| EP-4370522-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | Nikang Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| EP-4370206-A1 | ESTERS OF 7-COOH CBD DERIVATIVES AND THEIR USE AS PREVENTION, PROPHYLAXIS OF PROGRESSION, AND/OR TREATMENT OF NEUROGENERATIVE DISEASES | Receptorpharma Inc S-Corp (US) | 2024-05-22 | — | — | EP | claimed |
| CN-117980310-A | Alkylene derivatives as KRAS inhibitors | 尼坎治疗公司 | 2024-05-03 | — | — | CN | claimed |
| EP-4182323-B1 | PYRIDO OXAZINE AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARM SPA (IT) | 2024-04-24 | — | — | EP | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | claimed |
| EP-0567967-A1 | Tritium-labelled fibrinogen-receptor-antagonists, their use and their production | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0417555-B1 | Pentamethine dyes and derivatives | BAYER AG (DE) | 1993-11-03 | — | — | EP | claimed |
| WO-1993020078-A1 | PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES | THE UPJOHN COMPANY (US) | 1993-10-14 | — | — | WO | claimed |
| US-5091425-A | Inhibitors of the catalytic action of renin | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | claimed |
| EP-0417555-A1 | Pentamethine dyes and derivatives | BAYER AG (DE) | 1991-03-20 | — | — | EP | claimed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | claimed |
| EP-0369743-A2 | Heterocyclic amides | ZENECA LIMITED (GB) | 1990-05-23 | — | — | EP | claimed |
| US-4410536-A | 7,8,9,10-Tetrahydrothieno[3,2-e]pyrido[4,3-b]indole compounds and their anti-depressant use | TROPONWERKE GMBH & CO. K.G. (DE) | 1983-10-18 | — | — | US | claimed |
| EP-0065823-A1 | Heterocyclic guanidines as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |