SCHEMBL558744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL558440	0.82	KMO (0.46)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL558607	0.81	KMO (0.51)	CYP2D6KDM4EALDH1A1CYP1A2CYP3A4
	SCHEMBL17694991	0.75	ABL1 (0.50)	ABL1BCRGRM5MIFASIC3
	SCHEMBL558461	0.75	KMO (0.50)	GRM5MAP4K4KMO
	SCHEMBL27661815	0.73	ABL1 (0.38)	ABL1BCRGRM5MIFASIC3
	SCHEMBL558427	0.72	CYP1A2 (0.48)	LMNACYP2D6ALDH1A1TP53CYP1A2
	SCHEMBL558812	0.72	CYP1A1 (0.37)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL558366	0.72	MAPT (0.39)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL17694993	0.72	MAPT (0.52)	ABL1BCRGRM5MIFASIC3
	SCHEMBL17694984	0.72	MAPT (0.52)	ABL1BCRGRM5MIFASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.