Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792917 | 0.78 | KDM4E (0.41) | PTPN1EEF2KPLK1PLK2KDM4E | |
| SCHEMBL11738492 | 0.76 | EEF2K (0.41) | PTPN1EEF2KPLK1PLK2CDC25A | |
| SCHEMBL17935505 | 0.69 | CDC25A (0.45) | PTPN1EEF2KPLK1PLK2CDC25A | |
| SCHEMBL754972 | 0.69 | CDC25A (0.45) | PTPN1EEF2KPLK1PLK2CDC25A | |
| SCHEMBL11602759 | 0.68 | PLK1 (0.75) | PTPN1EEF2KPLK1PLK2CDC25A | |
| Water SCHEMBL28969836 | 0.67 | CDC25A (0.43) | PTPN1EEF2KPLK1PLK2CDC25A | |
| SCHEMBL18992936 | 0.67 | EEF2K (0.52) | PTPN1EEF2KPLK1PLK2CDC25A | |
| SCHEMBL13986038 | 0.65 | CDC25A (0.38) | PTPN1EEF2KPLK1PLK2CDC25A | |
| SCHEMBL12792912 | 0.65 | EEF2K (0.34) | PTPN1EEF2KPLK1PLK2 | |
| SCHEMBL6888742 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053468-A | PROCESS FOR PREPARING 7-OXO CEPHALOSPORINS AND 6-OXO PENICILLINS | SMITHKLINE CORPORATION (US) | 1977-10-11 | — | — | US | claimed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| US-4988754-A | Linear alternating copolymer of carbon monoxide, ethylene and an unsaturated olefin monomer with a stabilizing alkylated ben zoquinone | SHELL OIL COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0096392-B1 | NOVEL AMINOGLYCOSIDES, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF | KOWA COMPANY, LTD. (JP) | 1985-10-09 | — | — | EP | disclosed |
| US-4486418-A | ANTIBIOTICS | KOWA COMPANY, LTD. (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0096392-A1 | Novel aminoglycosides, process for production thereof and use thereof | KOWA COMPANY, LTD. (JP) | 1983-12-21 | — | — | EP | disclosed |
| US-4053468-A | PROCESS FOR PREPARING 7-OXO CEPHALOSPORINS AND 6-OXO PENICILLINS | SMITHKLINE CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | PTPN1 4679/4885EEF2K 2779/4885PLK1 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.