⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932594 | 0.65 | — | — | |
| SCHEMBL448317 | 0.65 | — | — | |
| SCHEMBL450465 | 0.65 | — | — | |
| SCHEMBL451629 | 0.65 | — | — | |
| SCHEMBL9170 | 0.65 | — | — | |
| SCHEMBL17474307 | 0.65 | — | — | |
| SCHEMBL672185 | 0.65 | — | — | |
| SCHEMBL4931800 | 0.62 | — | — | |
| SCHEMBL7106917 | 0.60 | — | — | |
| SCHEMBL558486 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | claimed |
| WO-2024009215-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-11 | — | — | WO | claimed |
| CN-111892601-B | Pyridopyrazolocinnoline compound and preparation method and application thereof | 陕西大美化工科技有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-111892597-B | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 山西天宏达安医药科技有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-111925370-A | Pyrazinopyrazolonaphthyridine compound and preparation method and application thereof | 朱继强 | 2020-11-13 | — | — | CN | claimed |
| CN-111892597-A | Quinoxalinyl pyridopyrazine compound and preparation method and application thereof | 朱继强 | 2020-11-06 | — | — | CN | claimed |
| CN-111892601-A | Pyridopyrazolo cinnoline compound and preparation method and application thereof | 朱继强 | 2020-11-06 | — | — | CN | claimed |
| EP-3157920-B1 | INDOLIZINE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-08-07 | — | — | EP | claimed |
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | claimed |
| EP-2986593-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2017-07-19 | — | — | EP | claimed |
| WO-1999066934-A1 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | claimed |
| CN-1202896-A | Purine derivatives and processes for their preparation | 诺瓦提斯公司 | 1998-12-23 | — | — | CN | claimed |
| EP-0539421-B1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1998-09-23 | — | — | EP | claimed |
| EP-0393738-B1 | Hydroxyalkylfuranyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1994-11-30 | — | — | EP | claimed |
| US-5278165-A | Oxazolyl imidazol[4,5-b]pyridin and pyrimidine compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-01-11 | — | — | US | claimed |
| EP-0539421-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-05 | — | — | EP | claimed |
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | claimed |
| EP-0393738-A1 | Hydroxyalkylfuranyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-10-24 | — | — | EP | claimed |
| EP-0096004-B1 | SULFONYL(THIO)UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR GROWTH REGULATING AGENTS | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | claimed |
| EP-0136266-A2 | 7-Beta-acylamido-3-cephem-4-carboxylic-acid esters, process for their preparation, pharmaceutical compositions and their application | CIBA-GEIGY AG (CH) | 1985-04-03 | — | — | EP | claimed |