SCHEMBL558900

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL558348	0.83	LMNA (0.73)	CRBNLMNAMAPK1ACP1SCD
	SCHEMBL558047	0.83	LCK (0.69)	CRBNLCKNPC1RAB9ASMN1; SMN2
	SCHEMBL22932498	0.80	CRBN (1.00)	CRBNLCK
	SCHEMBL25300197	0.78	LCK (0.52)	CRBNLCKL3MBTL1
	SCHEMBL31114503	0.78	LCK (0.52)	CRBNLCKL3MBTL1
	SCHEMBL32678287	0.78	LMNA (0.73)	LMNAMAPK1ACP1SCDNPC1
	SCHEMBL17090573	0.78	LCK (0.69)	ACP1LCKNPC1RAB9ASMN1; SMN2
	SCHEMBL2666847	0.78	DYRK1A (0.67)	LCKRAB9ADYRK1ADYRK1B
	SCHEMBL29506738	0.78	LCK (0.69)	ACP1LCKNPC1RAB9ASMN1; SMN2
	SCHEMBL32678120	0.78	LMNA (0.60)	CRBNLMNAMAPK1ACP1SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.