Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479197 | 0.89 | PDE4B (0.66) | PDE4B | |
| SCHEMBL2481386 | 0.87 | PDE4B (0.59) | PDE4BSYKTHRB | |
| SCHEMBL5590148 | 0.86 | PDE4B (0.60) | PDE4B | |
| SCHEMBL31020762 | 0.83 | PDE4B (0.54) | PDE4B | |
| SCHEMBL1275327 | 0.83 | PDE4B (0.66) | PDE4BSYK | |
| SCHEMBL1276200 | 0.82 | PDE4B (0.67) | PDE4B | |
| SCHEMBL2479181 | 0.80 | PDE4B (0.71) | PDE4B | |
| SCHEMBL1275589 | 0.80 | PDE4B (0.75) | PDE4B | |
| Hydrochloric Acid SCHEMBL2481486 | 0.79 | PDE4B (0.74) | PDE4B | |
| SCHEMBL4949711 | 0.79 | PDE4B (0.64) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007501264-A | — | — | 2007-01-25 | — | — | JP | claimed |
| EP-1633748-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-15 | — | — | EP | claimed |
| WO-2004103998-A1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-02 | — | — | WO | claimed |