Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12702676 | 0.88 | BACE1 (0.56) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL8009534 | 0.87 | BACE1 (0.53) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL8019435 | 0.87 | BACE1 (0.58) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL5590795 | 0.87 | PPARG (0.45) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL27639564 | 0.87 | PPARG (0.45) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL5590796 | 0.87 | PPARG (0.45) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL8011278 | 0.86 | BACE1 (0.55) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL27660340 | 0.86 | PTGES (0.46) | BACE1PPARGPPARDPPARADNMT1 | |
| SCHEMBL8023186 | 0.84 | BACE1 (0.52) | BACE1TSHRACHE | |
| SCHEMBL16224898 | 0.83 | PPARG (0.53) | BACE1PPARGPPARDPPARADNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007204431-A | FAT CELL DIFFERENTIATION PROMOTER | FUJI SANGYO KK | 2007-08-16 | — | — | JP | disclosed |