Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 18/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591060 | 0.91 | MPL (0.68) | MPLADORA3NEK2 | |
| SCHEMBL5591086 | 0.90 | MPL (0.58) | MPLADORA3 | |
| SCHEMBL5591096 | 0.90 | MPL (0.74) | MPL | |
| SCHEMBL5591104 | 0.89 | MPL (0.79) | MPL | |
| SCHEMBL5591118 | 0.88 | MPL (0.74) | MPL | |
| SCHEMBL5591212 | 0.86 | MPL (0.84) | MPL | |
| SCHEMBL5591002 | 0.86 | MPL (0.81) | MPL | |
| SCHEMBL5591090 | 0.85 | MPL (0.75) | MPL | |
| SCHEMBL5591107 | 0.83 | MPL (0.65) | MPL | |
| SCHEMBL5591001 | 0.83 | MPL (1.00) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | disclosed |