Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591160 | 0.91 | MPL (0.82) | MPL | |
| SCHEMBL5591632 | 0.91 | MPL (0.62) | MPL | |
| SCHEMBL5591071 | 0.88 | MPL (0.76) | MPL | |
| SCHEMBL5591024 | 0.87 | MPL (0.86) | MPL | |
| SCHEMBL5591095 | 0.87 | MPL (0.91) | MPL | |
| SCHEMBL5591088 | 0.87 | MPL (0.85) | MPL | |
| SCHEMBL5591094 | 0.86 | MPL (0.82) | MPL | |
| SCHEMBL5591329 | 0.86 | MPL (0.82) | MPL | |
| SCHEMBL5591028 | 0.86 | MPL (1.00) | MPL | |
| SCHEMBL5591114 | 0.85 | MPL (0.76) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | disclosed |