Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.65 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.64 |
| ▸ | OSBP | P22059 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | RORC | P51449 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.54 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 2/20 | 0.52 |
| ▸ | UGCG | Q16739 | 2/20 | 0.52 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912626 | 1.00 | POLA1 (0.65) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL9186861 | 0.93 | POLA1 (0.67) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL1296893 | 0.93 | POLA1 (0.75) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL9186858 | 0.90 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL4437346 | 0.90 | POLA1 (0.73) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL1296888 | 0.90 | POLA1 (0.73) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL2979168 | 0.90 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL1296890 | 0.90 | POLA1 (0.73) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL2979167 | 0.90 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL19460417 | 0.90 | POLA1 (0.73) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112593-A1 | Selection system, dispensing system and treatment with a one-a-day combination pill for hypertension, hypercholesterolemia, hypertriglyceridemia and anti-platelet treatment | RXCERA PHARMACEUTICAL, INC. | 2007-05-17 | — | — | US | disclosed |