Sugi Predict

Sugi Predict / Compounds / SCHEMBL4437346

SCHEMBL4437346

SCHEMBL4437346

CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC=C4CC(OC(=O)c5ccccc5C(=O)O)CC[C@]4(C)C3CC[C@@]21C

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ POLA1 P09884 1/20 0.73
▸ CYP46A1 Q9Y6A2 2/20 0.67
▸ OSBP P22059 3/20 0.63
▸ USP2 O75604 2/20 0.63
▸ RORC P51449 2/20 0.63
▸ LMNA P02545 1/20 0.63
▸ ABCB1 P08183 1/20 0.63
▸ OSBP2 Q969R2 1/20 0.63
▸ NPC1L1 Q9UHC9 4/20 0.57
▸ NPC1 O15118 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ GBA1 P04062 2/20 0.56
▸ UGCG Q16739 2/20 0.56
▸ GBA2 Q9HCG7 2/20 0.56
▸ NR1H3 Q13133 3/20 0.56
▸ EPHA2 P29317 1/20 0.55
▸ GRIN1 Q05586 1/20 0.54
▸ GRIN2A Q12879 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19460417 1.00 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1296890 1.00 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1296888 1.00 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL1296893 0.97 POLA1 (0.75) POLA1CYP46A1OSBPUSP2RORC
Ether SCHEMBL7529582 0.96 POLA1 (0.68) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL4660535 0.93 POLA1 (0.68) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL28207876 0.92 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL2979167 0.92 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL2979168 0.92 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL9186858 0.92 POLA1 (0.69) POLA1CYP46A1OSBPUSP2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2136856-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY Miv Therapeutics Inc. (CA) 2009-12-30 — — EP claimed
US-20080181928-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY MIV THERAPEUTICS, INC. (CA) 2008-07-31 — — US claimed
WO-2008077247-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL MIV THERAPEUTICS INC. (CA) 2008-07-03 — — WO claimed
WO-2008077248-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY MIV THERAPEUTICS INC. (CA) 2008-07-03 — — WO claimed
US-11918770-B2 Implants for localized drug delivery and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-05 — — US disclosed
CN-109478389-B Multi-layer display with color and contrast enhancement 三星电子株式会社 2023-01-10 — — CN disclosed
US-20220184362-A1 Implants for Localized Drug Delivery and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-06-16 — — US disclosed
US-11324935-B2 Implants for localized drug delivery and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-10 — — US disclosed
CN-109477972-B Multi-layer high transparency display for light field generation 三星电子株式会社 2022-02-22 — — CN disclosed
CN-111433577-B Temperature detection label and article management device using same 株式会社日立制作所 2021-09-21 — — CN disclosed
CN-110603431-B Temperature detection material, temperature detection ink using same, temperature indicator, and article management system 株式会社日立产机系统 2021-06-15 — — CN disclosed
US-10912933-B2 Implants for localized drug delivery and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-09 — — US disclosed
EP-0467954-A1 PREPARATION OF LIPOSOME AND LIPID COMPLEX COMPOSITIONS. UNIV CALIFORNIA (US) 1992-01-29 — — EP disclosed
US-5077057-A Dissolving in aprotic solvent; extrusion into aqueous solution THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-12-31 — — US disclosed
WO-1990011780-A1 PREPARATION OF LIPOSOME AND LIPID COMPLEX COMPOSITIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-10-18 — — WO disclosed
US-4247597-A Electroscopic carrier particles having a carboxylic acid surface treatment PITNEY BOWES, INC. (US) 1981-01-27 — — US disclosed
US-4183847-A STANDARD FOR DETERMING CHOLESTEROL CONTENT MONOBIND, INC., A CORP. OF CA. 1980-01-15 — — US disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 — — US disclosed
US-4042330-A In a method for checking the accuracy of a test using an enzymatically hydrolyzable, serum-soluble cholesterol compound MONOBIND, INC., A CORP. OF CA. 1977-08-16 — — US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181928-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY LIPA, SGMS2, SGMS1 POLA1 4883/4885CYP46A1 357/4885OSBP 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.