Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244869 | 0.98 | STK17B (0.39) | STK17BSTK17ACACNA1BAAK1CNR2 | |
| SCHEMBL5302024 | 0.90 | STK17B (0.44) | STK17BSTK17ACACNA1BCNR2JAK3 | |
| SCHEMBL5305110 | 0.85 | CTSS (0.42) | CACNA1BAAK1CNR2JAK3BTK | |
| SCHEMBL5305633 | 0.84 | CTSS (0.43) | CACNA1BCNR2JAK3BTK | |
| SCHEMBL5309318 | 0.83 | CTSS (0.40) | AAK1CNR2JAK3BTKIGF1R | |
| SCHEMBL3174379 | 0.83 | STK17B (0.39) | STK17BSTK17ACACNA1BAAK1JAK3 | |
| SCHEMBL3176616 | 0.83 | STK17B (0.42) | STK17BSTK17AAAK1CKS1BSKP1 | |
| SCHEMBL3169517 | 0.82 | STK17B (0.38) | STK17BSTK17ACACNA1BAAK1JAK3 | |
| SCHEMBL5304940 | 0.81 | STK17B (0.41) | STK17BSTK17AAAK1CKS1BSKP1 | |
| SCHEMBL3316282 | 0.81 | STK17B (0.41) | STK17BSTK17AAAK1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025774-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |