Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439395 | 0.82 | GRM4 (0.46) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL568374 | 0.81 | GRM4 (0.48) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL31220043 | 0.79 | THRB (0.33) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL4993025 | 0.77 | GRM4 (0.51) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL3439397 | 0.74 | GRM4 (0.46) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL2574273 | 0.73 | GRM4 (0.48) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL29493429 | 0.73 | GAA (0.53) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL422433 | 0.73 | GRM4 (0.48) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL1278809 | 0.73 | MEN1 (0.54) | GRM4MEN1KMT2ACA1CA2 | |
| SCHEMBL27463601 | 0.73 | GRM4 (0.51) | GRM4MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034277-A1 | ARYL SUBSTITUTED IMIDAZO [4,5-C] PYRIDINE COMPOUNDS AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |