Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24320209 | 0.83 | PTGER4 (0.53) | PTGER4TP53LMNAITKKMT2A | |
| SCHEMBL28971006 | 0.81 | KDM4E (0.59) | PTGER4TDP1LMNAKMT2AHTT | |
| SCHEMBL20206661 | 0.79 | TDP1 (0.48) | PTGER4TDP1BRD4TP53LMNA | |
| SCHEMBL25828246 | 0.77 | GALR3 (0.49) | PTGER4BRD4TP53KMT2AALDH1A1 | |
| SCHEMBL10953589 | 0.76 | KDM4E (0.50) | TP53LMNAMAPTKMT2AHTT | |
| SCHEMBL15774493 | 0.75 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL5009001 | 0.75 | HPGD (0.70) | TP53LMNAKMT2AHPGDHTT | |
| SCHEMBL16806042 | 0.75 | MAPT (0.62) | TDP1BRD4TP53LMNAMAPT | |
| SCHEMBL16806040 | 0.73 | KDM4E (0.50) | PTGER4TDP1BRD4TP53LMNA | |
| SCHEMBL28593699 | 0.72 | KDM4E (0.48) | PTGER4TDP1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |