Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302212 | 0.85 | KMT2A (0.47) | ALOX5APPTGER4KMT2AJAK2JAK1 | |
| SCHEMBL28971006 | 0.77 | KDM4E (0.59) | PTGER4KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL5591608 | 0.77 | PTGER4 (0.59) | TP53PTGER4KMT2ABRD4KDM4E | |
| SCHEMBL30581464 | 0.77 | ITK (0.45) | ALOX5APKDM4EALDH1A1 | |
| SCHEMBL25257056 | 0.77 | ITK (0.45) | ALOX5APKDM4EALDH1A1 | |
| SCHEMBL30581453 | 0.76 | ALOX5AP (0.34) | GALR3NR2F2ALOX5APPTGER4BRD4 | |
| SCHEMBL30581444 | 0.75 | ITK (0.58) | TP53KMT2AKDM4EALDH1A1 | |
| SCHEMBL25296139 | 0.75 | ITK (0.58) | TP53KMT2AKDM4EALDH1A1 | |
| SCHEMBL25299930 | 0.75 | ALDH1A1 (0.46) | GALR3NR2F2ALOX5APKMT2APOLB | |
| SCHEMBL30586461 | 0.75 | ALDH1A1 (0.46) | GALR3NR2F2ALOX5APKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |