Diphenylmethane

Diphenylmethane

SCHEMBL5591702

N=C=N.N=C=N.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.75
LTA4H P09960 1/20 0.48
MAOB P27338 1/20 0.48
IDH1 O75874 1/20 0.46
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
PLA2G10 O15496 1/20 0.44
PLA2G2A P14555 1/20 0.44
LMNA P02545 1/20 0.44
BCL2 P10415 1/20 0.44
BCL2L1 Q07817 1/20 0.44
TSHR P16473 2/20 0.43
IDO1 P14902 1/20 0.43
TP53 P04637 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43
SLC22A2 O15244 1/20 0.43
TRPA1 O75762 1/20 0.43
ALDH1A1 P00352 1/20 0.43
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL5433494 1.00 CALM1 (0.75) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL29048087 0.92 CALM1 (0.63) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL4395007 0.92 CALM1 (0.63) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL28763356 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL9449990 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL15415 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL10593337 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL28457396 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL333766 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1
Diphenylmethane SCHEMBL465158 0.88 CALM1 (0.67) CALM1LTA4HMAOBIDH1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220536-B2 Silver salt photothermographic dry imaging material, thermal development method of the same, and thermal development apparatus for the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-22 US disclosed
US-7105288-B2 Mixture of organosilvr compound, sailver halide emulsion and reducing agents KONICA CORPORATION (JP) 2006-09-12 US disclosed
US-20060088785-A1 Silver salt photothermographic dry imaging material, thermal development method of the same, and thermal development apparatus for the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-04-27 US disclosed
US-20040043341-A1 Silver salt photothermographic dry imaging material KONICA CORPORATION (JP) 2004-03-04 US disclosed