Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.48 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591921 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4ECYP19A1WNK1 | |
| SCHEMBL5591846 | 0.86 | CYP11B1 (0.52) | SMN1; SMN2ALDH1A1CYP19A1MAPTMEN1 | |
| SCHEMBL14423559 | 0.86 | CYP19A1 (0.58) | SMN1; SMN2ALDH1A1KDM4ECYP19A1MAPT | |
| SCHEMBL5591937 | 0.85 | CYP19A1 (0.63) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5591889 | 0.85 | CYP19A1 (0.63) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL14423359 | 0.84 | CYP11B1 (0.52) | SMN1; SMN2CYP19A1MAPTMEN1HTT | |
| SCHEMBL5591934 | 0.83 | CYP19A1 (0.55) | SMN1; SMN2ALDH1A1KDM4ECYP19A1MAPT | |
| SCHEMBL5591722 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KDM4ECYP19A1MAPT | |
| SCHEMBL5591829 | 0.80 | CYP19A1 (0.56) | ALDH1A1KDM4ECYP19A1MAPTCYP11B1 | |
| SCHEMBL5591843 | 0.78 | CYP19A1 (0.49) | SMN1; SMN2ALDH1A1CYP19A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |