Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | LSS | P48449 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591889 | 1.00 | CYP19A1 (0.63) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL14423559 | 0.95 | CYP19A1 (0.58) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL5591829 | 0.94 | CYP19A1 (0.56) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL5591821 | 0.89 | CYP19A1 (0.51) | CYP19A1KDM4EALDH1A1LSS | |
| SCHEMBL5591843 | 0.87 | CYP19A1 (0.49) | CYP19A1ALDH1A1 | |
| SCHEMBL5591805 | 0.87 | CYP19A1 (0.48) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL5591943 | 0.87 | CYP19A1 (0.51) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL14423359 | 0.86 | CYP11B1 (0.52) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5591886 | 0.85 | SMN1; SMN2 (0.49) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL5591934 | 0.85 | CYP19A1 (0.55) | CYP19A1KDM4EALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |