Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445668 | 0.86 | PARP1 (0.63) | TDP1PARP1ATML3MBTL1ALOX15 | |
| SCHEMBL3173817 | 0.86 | PARP1 (0.68) | TDP1PARP1ATML3MBTL1ALOX15 | |
| SCHEMBL31514279 | 0.84 | ATM (0.71) | TDP1PARP1ATML3MBTL1ALOX15 | |
| SCHEMBL1133114 | 0.84 | ATM (0.71) | TDP1PARP1ATML3MBTL1ALOX15 | |
| SCHEMBL3444927 | 0.84 | PARP1 (0.65) | TDP1PARP1ATML3MBTL1ALOX15 | |
| SCHEMBL3177794 | 0.82 | PARP1 (0.59) | TDP1PARP1ATML3MBTL1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL28227232 | 0.82 | ATM (0.68) | TDP1PARP1ATML3MBTL1ALOX15 | |
| SCHEMBL15646031 | 0.82 | PKM (0.64) | MEN1KMT2ASMN1; SMN2GRM5PKM | |
| SCHEMBL7488057 | 0.79 | MAPK1 (0.64) | MEN1KMT2ATDP1SMN1; SMN2PARP1 | |
| SCHEMBL8437706 | 0.79 | SRD5A2 (0.64) | TDP1PARP1ATML3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |