Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567082 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL6466443 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL25374549 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL21800166 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL5819225 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL8431899 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL8431893 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL9207207 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL3016113 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL7675096 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HTTLMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007125398-A2 | : SULFONAMIDE COMPOUNDS AS ANTAGONISTS OF THE N-TYPE CALCIUM CHANNEL | PFIZER JAPAN INC. (JP) | 2007-11-08 | — | — | WO | disclosed |