Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977875 | 0.76 | ALDH1A1 (0.45) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL473919 | 0.74 | ALDH1A1 (0.51) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL15202917 | 0.74 | TDP1 (0.50) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL29726958 | 0.74 | ALDH1A1 (0.51) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL13977503 | 0.73 | ALDH1A1 (0.39) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL230989 | 0.71 | KMT2A (0.45) | TDP1ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL8337219 | 0.70 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL454098 | 0.70 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL31050105 | 0.70 | ALDH1A1 (0.61) | TDP1ALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL337203 | 0.70 | ALDH1A1 (0.61) | TDP1ALDH1A1MAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |