Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493377 | 0.88 | HSD11B1 (0.74) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3646334 | 0.84 | HSD11B1 (0.68) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10672820 | 0.82 | HSD11B1 (0.66) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL4675275 | 0.82 | HSD11B1 (0.64) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10670995 | 0.81 | HSD11B1 (0.64) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10677744 | 0.79 | HSD11B1 (0.63) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL5592634 | 0.79 | HSD11B1 (0.62) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL2968359 | 0.79 | HSD11B1 (0.61) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL2968355 | 0.79 | HSD11B1 (0.61) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL5542401 | 0.79 | HSD11B1 (0.62) | HSD11B1PKMHTTNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |