Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TEK | Q02763 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 4/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622327 | 0.95 | RAF1 (0.48) | RAB9ANPC1TEKRAF1BRAF | |
| SCHEMBL14473337 | 0.94 | RAB9A (0.46) | RAB9ANPC1TEKRAF1BRAF | |
| SCHEMBL4420145 | 0.90 | RAB9A (0.45) | RAB9ANPC1TEKRAF1BRAF | |
| SCHEMBL4417393 | 0.88 | TEK (0.50) | TEKRAF1BRAFCSF1RLMNA | |
| SCHEMBL4417623 | 0.88 | TEK (0.51) | TEKRAF1BRAFCSF1R | |
| SCHEMBL14473113 | 0.87 | TEK (0.41) | RAB9ANPC1TEKRAF1BRAF | |
| SCHEMBL14473326 | 0.87 | RAB9A (0.51) | RAB9ANPC1RAF1BRAFALDH1A1 | |
| SCHEMBL14473153 | 0.86 | TEK (0.53) | RAB9ATEKRAF1BRAFCSF1R | |
| SCHEMBL5593020 | 0.85 | RAB9A (0.49) | RAB9ANPC1TEKRAF1BRAF | |
| SCHEMBL4412491 | 0.83 | TEK (0.57) | TEKRAF1BRAFCSF1RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |