Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 14/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593377 | 0.94 | EGLN2 (0.38) | PDE2ALMNAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5593349 | 0.91 | PDE2A (0.42) | PDE2ALMNAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5593199 | 0.90 | LMNA (0.40) | PDE2ALMNAALDH1A1GLATSHR | |
| SCHEMBL5593160 | 0.89 | LMNA (0.43) | PDE2ALMNAALDH1A1GLATSHR | |
| SCHEMBL5593162 | 0.89 | SMN1; SMN2 (0.40) | PDE2ALMNAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5593136 | 0.87 | PDE2A (0.39) | PDE2ALMNAGLATSHRNPSR1 | |
| SCHEMBL5593163 | 0.85 | PDE2A (0.40) | PDE2ALMNAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL5593567 | 0.85 | PDE2A (0.39) | PDE2A | |
| SCHEMBL5593381 | 0.85 | EGLN2 (0.41) | PDE2ALMNAHSD17B10ALDH1A1GLA | |
| SCHEMBL5593098 | 0.84 | PDE2A (0.44) | PDE2ALMNAPOLBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |