Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477740 | 0.82 | TDP1 (0.53) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL15354396 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL30222343 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL4796250 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL4034382 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL17061698 | 0.80 | SLC6A4 (0.44) | SLC6A2SLC6A3SLC6A4SCN9AMAPT | |
| SCHEMBL25598529 | 0.79 | SLC6A2 (0.47) | TDP1SLC6A2SLC6A3SLC6A4MAPT | |
| SCHEMBL27573895 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL3289147 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNATDP1CYP19A1 | |
| SCHEMBL25598585 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1LMNATDP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007083090-A2 | PROCESS FOR THE PREPARATION OF URACIL DERIVATIVES | SYNGENTA LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007083090-A2 | PROCESS FOR THE PREPARATION OF URACIL DERIVATIVES | SYNGENTA LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |