Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31614569 | 0.90 | VCP (0.68) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL5592873 | 0.90 | VCP (0.68) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL30114955 | 0.89 | VCP (0.58) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL28972874 | 0.89 | VCP (0.58) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL15827958 | 0.84 | VCP (1.00) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL5593353 | 0.83 | VCP (0.63) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL25749196 | 0.82 | VCP (0.82) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL5592874 | 0.80 | VCP (0.68) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL30114847 | 0.80 | VCP (0.68) | VCPALDH1A1HSP90AA1MAPTNPSR1 | |
| SCHEMBL28972916 | 0.80 | VCP (0.67) | VCPALDH1A1HSP90AA1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | disclosed |