Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593197 | 0.99 | EGLN2 (0.40) | EGLN2ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL5593478 | 0.95 | EGLN2 (0.41) | EGLN2ALDH1A1TSHRPDE2AALOX15 | |
| SCHEMBL5593414 | 0.88 | MAPT (0.38) | EGLN2ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL5593106 | 0.87 | TSHR (0.38) | ALDH1A1TSHRCDK2GSK3BPDE2A | |
| SCHEMBL5593450 | 0.87 | MAPT (0.39) | EGLN2CDK2GSK3BPDE2AMEN1 | |
| SCHEMBL5593138 | 0.86 | MAPK1 (0.39) | TSHRCDK2GSK3BPDE2AALOX15 | |
| SCHEMBL5593267 | 0.85 | CDK2 (0.35) | ALDH1A1TSHRCDK2GSK3BPDE2A | |
| SCHEMBL5593251 | 0.84 | TSHR (0.35) | EGLN2ALDH1A1TSHRCDK2GSK3B | |
| SCHEMBL5593468 | 0.84 | CDK2 (0.34) | EGLN2TSHRCDK2GSK3BPDE2A | |
| SCHEMBL5593402 | 0.83 | EGLN2 (0.39) | EGLN2HPGDPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |