Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593450 | 0.96 | MAPT (0.39) | EGLN2PDE2AKDM1AMAPT | |
| SCHEMBL5593414 | 0.95 | MAPT (0.38) | EGLN2PDE2AMAPTHPGD | |
| SCHEMBL5593478 | 0.87 | EGLN2 (0.41) | EGLN2PDE2A | |
| SCHEMBL5593147 | 0.86 | PDE2A (0.36) | EGLN2PDE2AIRAK4CYP1A2HPGD | |
| SCHEMBL5593060 | 0.86 | CYP1A2 (0.39) | PDE2AIRAK4CYP1A2HPGD | |
| SCHEMBL5593148 | 0.85 | PDE2A (0.36) | EGLN2PDE2AIRAK4CYP1A2HPGD | |
| SCHEMBL5593197 | 0.84 | EGLN2 (0.40) | EGLN2PDE2AHPGD | |
| SCHEMBL5593059 | 0.83 | EGLN2 (0.35) | EGLN2CYP1A2HPGD | |
| SCHEMBL5593433 | 0.83 | EGLN2 (0.39) | EGLN2PDE2AHPGD | |
| SCHEMBL5593351 | 0.83 | PDE2A (0.37) | PDE2AIRAK4CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |