Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593163 | 0.95 | PDE2A (0.40) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593364 | 0.90 | LMNA (0.42) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593199 | 0.90 | LMNA (0.40) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593349 | 0.90 | PDE2A (0.42) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593288 | 0.89 | PDE2A (0.39) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593514 | 0.89 | SMN1; SMN2 (0.40) | PDE2ATSHRLMNAALDH1A1CYP1A2 | |
| SCHEMBL5593357 | 0.87 | KDM1A (0.41) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593245 | 0.85 | PDE2A (0.40) | PDE2ACYP1A2EGLN2 | |
| SCHEMBL5593377 | 0.85 | EGLN2 (0.38) | PDE2ATSHRNPSR1GLALMNA | |
| SCHEMBL5593398 | 0.85 | PDE2A (0.42) | PDE2ATSHRNPSR1GLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |