Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318957 | 0.99 | HTT (0.45) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL10493810 | 0.89 | HSD17B10 (0.49) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL9770175 | 0.89 | HSD17B10 (0.49) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL10493808 | 0.87 | HSD17B10 (0.50) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL5232567 | 0.82 | MAPT (0.44) | HTTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9770335 | 0.75 | HSD17B10 (0.56) | HTTSMN1; SMN2HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL8944181 | 0.74 | GAA (0.47) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL8943804 | 0.74 | GAA (0.47) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL8944386 | 0.74 | GAA (0.47) | HTTSMN1; SMN2GAAATMHSD17B10 | |
| SCHEMBL8944393 | 0.74 | GAA (0.47) | HTTSMN1; SMN2GAAATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116011-A2 | SUBSTITUTED TRIAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF FOR CONTROLLING HARMFUL FUNGI, AND SUBSTANCES CONTAINING THE SAME | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |