SCHEMBL9770335

SCHEMBL9770335

Cc1nc2ncnn2c(O)c1CCc1c(C)nc2ncnn2c1O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.56
ENPP1 P22413 6/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 3/20 0.48
USP2 O75604 1/20 0.48
HTT P42858 2/20 0.46
MAPK1 P28482 1/20 0.46
TSHR P16473 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP3A4 P08684 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12769185 0.92 HSD17B10 (0.52) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL10493808 0.89 HSD17B10 (0.50) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL5197330 0.88 MEN1 (0.55) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL9770175 0.88 HSD17B10 (0.49) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL10493810 0.88 HSD17B10 (0.49) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL9824149 0.82 HSD17B10 (0.46) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL10623162 0.81 HSD17B10 (0.43) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL9824226 0.81 ALDH1A1 (0.44) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL5199168 0.80 TSHR (0.50) HSD17B10ENPP1L3MBTL1ALDH1A1USP2
SCHEMBL24128962 0.78 ENPP1 (0.53) ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4011083-A SURFACE SENSITIVE SILVER HALIDE EMULSION CONTAINING A SILVER COMPLEXING AZAINDENE TO REDUCE DESENSITIZATION OF OPTICAL SENSITIZING DYE INCORPORATED THEREIN EASTMAN KODAK COMPANY (US) 1977-03-08 US claimed
US-5015567-A Sensitization In The Presence Of An Organic Thioether Or A Tetra-substituted Thiourea And A Triazolopyrimidine Stabilizer FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-4011083-A SURFACE SENSITIVE SILVER HALIDE EMULSION CONTAINING A SILVER COMPLEXING AZAINDENE TO REDUCE DESENSITIZATION OF OPTICAL SENSITIZING DYE INCORPORATED THEREIN EASTMAN KODAK COMPANY (US) 1977-03-08 US disclosed