SCHEMBL5594445

SCHEMBL5594445

BrCCNc1ccc2ccccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.64
ALDH1A1 P00352 3/20 0.64
CYP3A4 P08684 2/20 0.64
HSD17B10 Q99714 2/20 0.64
CYP2C19 P33261 2/20 0.64
HIF1A Q16665 2/20 0.64
CYP2D6 P10635 1/20 0.64
CYP2C9 P11712 1/20 0.64
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 3/20 0.49
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HPGD P15428 1/20 0.48
INSR P06213 1/20 0.47
IGF1R P08069 1/20 0.47
PPARG P37231 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11605746 0.87 CYP1A2 (0.75) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL4168758 0.82 ALDH1A1 (0.67) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL11446069 0.80 ALDH1A1 (0.64) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL8099994 0.80 ALDH1A1 (0.64) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL11651781 0.80 ALDH1A1 (0.64) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL4341824 0.80 CYP1A2 (0.64) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL8808326 0.80 ALDH1A1 (0.64) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
SCHEMBL30447073 0.80 ALDH1A1 (0.64) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
Ammonia Solution, Strong SCHEMBL8652657 0.78 ALDH1A1 (0.62) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19
Hydrochloric Acid SCHEMBL31741338 0.78 ALDH1A1 (0.62) CYP1A2ALDH1A1CYP3A4HSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007022263-A1 FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2007-02-22 WO disclosed